Basis
Basis
NAD+ Supplement for Cellular Aging.
Target aging at the source—your cells. Increase your NAD+ levels with Basis for healthy aging, to boost cellular energy, and maintain healthy DNA.
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“I believe Basis is a product that can improve cellular health and target, at least, some of the deficits incurred by aging. It is an important part of a strategy that I follow, along with exercise and a healthy diet, to maintain an active life as I enter my seventies, and hopefully much longer.”
NAD+ Levels and Healthy Aging go Hand-in-Hand
esearch published in Nature Aging “suggests that a clear association exists between NAD+ and health status in human aging.” NAD+ (nicotinamide adenine dinucleotide) is found in every cell in your body. It is essential to the chemistry that keeps you up and running.
Unfortunately, NAD+ levels decline universally as we age.
How can you increase your NAD+ levels? Basis is the evidence-based choice
We now have a way to safely and sustainably boost NAD+ levels. Developed by Dr. Leonard Guarente, a leader in the field of aging research, Basis was clinically proven to increase NAD+ levels by an average of 40% in a double-blind, randomized
Boosted NAD+ activates sirtuins, supports cellular energy and metabolism, targets cellular aging to promote a healthy cellular aging process, and helps maintain healthy DNA.
Key Ingredients
Nicotinamide Riboside (NR-E)
It is a form of Vitamin B3 and a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme vital to support cellular aging.
Pterostilbene (PT)
A powerful polyphenol naturally produced by certain berries to protect against internal and external stress. It serves as a powerful antioxidant.
- Vegetarian
- Vegan
- Gluten-free
- Nut-free
- No artificial colors
- No artificial flavors
Suggested Use
Take two capsules in the morning, with or without food.
Each pouch contains a 30-day supply.
Basis benefits
- Promote healthy aging, feel good for your age
- Promote cellular energy and reduce general tiredness and fatigue
- Fight aging at the cellular level and protect your DNA from stressors
- Support collagen and ceramide synthesis for healthy skin
- Support healthy muscle function
Basis Journey
HOUR 4
You just took Basis-nothing could be happening yet, right? Actually, the nicotinamide riboside isalready making big moves. It enters your cells via equilibrative nucleoside transporters, membraneproteins that shuttle molecules across. *Individual results may vary. This timeline may differ from the typical purchaser's experience and is notintended to represent or guarantee that anyone will receive the same or similar results.
DAY 01
NAD+ levels are already on the rise at the cellular level. You can expect support for increased cellular energy, improved mitochondrial function, housekeeping for your proteome and genome, and cellular protection from everyday stressors (for example, oxidative stress). Not bad for a day's work.
DAY 14
As you take your daily serving, your cellular NAD+ levels steadily climb, spreading across every system throughout your whole body. Maintain your regular lifestyle and daily routines, as Basis quietly goes to work behind the scenes to support your long‑term cellular wellness.
DAY 30
Now results are really adding up. If you had all the gear for NAD+ analysis from whole-blood lysate,you could see for yourself. (Instead you can read our scientific paper.) Your cellular NAD+ levels arenow 40% higher than they were on day one, and that's where they'll stay if you keep taking Basis.Where is all this NAD+ going? Studies suggest that NR supplementation increases NAD+ and affectsNAD+-related metabolites in multiple tissues at 30 days-including your muscle and brain.
DAY 60
You've logged 30 days of elevated and sustained NAD+ levels in your cells and tissues. That's a big deal because 330 billion cells turn over each day. Colon epithelial cells, for example, turn over in 3-5days while the upper layer of the skin, or the epidermis, takes roughly 39 days to regenerate. NAD+can help with supporting these processes and tissue health. In your skin, more NAD+ can support theprocess of synthesizing ceramide and collagen. Our first human clinical trial on Basis also showedpreliminary evidence for supporting liver health and results from our latest, 6-month, human clinicalstudy (published in Hepatology) confirmed these initial findings in healthy adults with non-alcoholic fatty liver.
DAY 180
A lot happens in six months. What's changed in your life? With Basis, it's all starting to add up-to example, one study showed that six months of increased NAD+ levels reduced transepidermal water systemic health benefits. Basis is supporting multiple tissues and systems, in a sustained manner. For loss-a measure of overall skin health and barrier function.
BEYOND
Congratulations on your first year. NAD+ declines by as much as 50% every 20 years, according toresearch. But human studies are beginning to show an association between NAD+ abundance andhealthy aging status. Keep taking Basis to counteract the age-related decline of NAD+ and to build ona year's worth of benefits. Just like with exercise, sleep, and diet-consistency is key.
Who it’s for
- Adults concerned about biological aging and cellular health
- Men & women seeking to support natural NAD+ levels which decline with age
- Busy adults with modern‑day lifestyles, looking for convenient daily longevity support
- Health‑conscious people maintaining fitness, diet and wellness routines
- Middle‑age adults wanting to support long‑term cellular function
Basis 101: The Science
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What is NAD+ and Why Is it Important?
NAD+ is essential to the creation of energy in the body and the regulation of pivotal cellular processes.
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What Is Nicotinamide Riboside?
This form of Vitamin B could be the key to restoring NAD+ levels .
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What is Pterostilbene?
A cousin to resveratrol but more potent—pterostilbene is found in certain berries and nuts and serves as a powerful antioxidant.
Frequently Asked Questions
Why are sirtuins important for aging?
Why are sirtuins important for aging?
Sirtuins are a family of proteins that regulate cellular health. Sirtuins play a key role in regulating cellular homeostasis. Homeostasis involves keeping the cell in balance. However, sirtuins can only function in the presence of NAD+, nicotinamide adenine dinucleotide, a coenzyme found in all living cells.
What is Nicotinamide Adenine Dinucleotide (NAD+) and why is it important?
What is Nicotinamide Adenine Dinucleotide (NAD+) and why is it important?
NAD+, or nicotinamide adenine dinucleotide, is a critical coenzyme found in every cell in your body, and it’s involved in hundreds of metabolic processes — but NAD+ levels decline with age. NAD+ has two general sets of reactions in the human body: Helping turn nutrients into cellular energy as a key player in metabolism and working as a helper molecule for proteins that regulate other cellular functions. These processes are incredibly important.
What is Nicotinamide Riboside (NR) and why is it important?
What is Nicotinamide Riboside (NR) and why is it important?
This form of Vitamin B could be the key to increasing NAD+ levels — here’s why. Nicotinamide riboside is often called NR for short, and it’s a precursor to NAD+, meaning it's the raw material from which your body makes NAD+ through a series of chemical transformations. Human clinical studies, including ours, have shown efficacy ofNR supplements in increasing NAD+ levels.
What is Pterostilbene and why is it important?
What is Pterostilbene and why is it important?
Pterostilbene is a polyphenol, a type of molecule that occurs in plants, particularly small berries and nuts. Blueberries are a particularly rich source of pterostilbene; although it is found in grapes, pterostilbene (unlike its cousin resveratrol) doesn’t survive the wine-making process.
What’s a polyphenol?
What’s a polyphenol?
“Phenol” refers to a certain chemical structure (in this case, a hydroxyl group linked to a benzene ring); “poly” just means the molecules have more than one of the structure. One of polyphenols’ main jobs is to help the plant fight off pathogens. When eaten by humans, polyphenols may serve as powerful antioxidants.
Is there anything I should notice once I start taking Basis?
Is there anything I should notice once I start taking Basis?
Basis is designed to work beneath the surface, so its primary purpose is not to deliver surface-level results. Taking Basis is an investment in the long-term health of your cells, and you may not feel different despite the improvements happening inside your body. Everyone’s physiology is unique and results vary from person to person.